One question we've been asked since the launch of Acrobat X is where the "Create PDF > From Blank Page" menu item's gone.
It's still there, kindof, just not on the menu. Instead, open the Tools Pane and under Pages > More Insert Options choose Insert Blank Page (Shift-Ctrl-Q or Shift-CMD-Q). If there's no document open this will create a new blank PDF. Unlike in Acrobat 9, there is no automatic text box applied to the new page.